Department of Physics - Université de Montréal

The Blunck Laboratory

In the Blunck lab we are studying the molecular mechanisms underlying the function of ion channels and pore forming toxins. Ion channels are modular membrane proteins with a central ion conducting domain that is regulated by peripheral "gating"domains sensitive to external stimuli such as membrane potential or ligands. We use in particular various fluorescence spectroscopic methods, including voltage-clamp fluorometry and single molecule fluorescence, to study the structure and function of the proteins of interest. One focus lies on new method development. Please read more here.



Research Interests

Please read more about our research interests here.



Last Publication:

The S4-S5 linker movement during activation and inactivation in voltage-gated K+ channels.
Kalstrup & Blunck, PNAS 2018 10.1073/pnas.1719105115 )


Progressive Internalization and Filtering (McGuire et al., JBC 2012)

PIF - Progressive Internalization and Filtering

PIF is a software suite for automated analysis of single subunit counting data.

(McGuire et al., J Biol Chem 2012)

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